| ncRNA name | hsa-miR-146b-5p |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB samples, retinas; RB cell lines Y79 and WERI-RB1 |
| Methods | qRT-PCR |
| Expression pattern | down-regulated |
| Functional description | Nearly 1948 miRNAs were identified in the in silico analysis, From this list, only 9 upregulated miRNAs and 10 downregulated miRNAs were found to be common with the RB serum miRNA profile. Downregulation of five miRNAs (miR-146b-5p, miR-532-5p, miR-142-5p, miR-328, and miR-486-3p) was confirmed experimentally. |
| PubMed ID | 25983556 |
| Year | 2015 |
| Title | Computational and in vitro Investigation of miRNA-Gene Regulations in Retinoblastoma Pathogenesis: miRNA Mimics Strategy. |
| Drug-related ncRNA | NO |
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